| 1878 | W | Amherst (MA) | 1 | Williston Seminary (MA) | 0 | ? | Amherst 1g,2t - Williston Academy 0 |
| 1878 | L | Amherst (MA) | 0 | Yale (CT) | 2 | New Haven, CT | Yale 2g,3t - Amherst 0 |
| 1878 | L | Amherst (MA) | 0 | Harvard (MA) | 3 | Amherst, MA | Harvard 3g,6t - Amherst 0 |
| 1878 | W | Amherst (MA) | 1 | Brown (RI) | 0 | Providence, RI | Amherst 1g,4t - Brown 0 |
| 1878 | T | Amherst (MA) | 0 | Yale (CT) | 0 | ? | Amherst 13s - Yale 1s |
| 1878 | L | Brown (RI) | 0 | Amherst (MA) | 1 | Providence, RI | Amherst 1g,4t - Brown 0 |
| 1878 | W | City College of New York | 7 | Seawanhakas Football Club (NY) | 0 | ? | City College of New York 7g,7t - Seawanhakas Football Club 0 |
| 1878 | L | City College of New York | 0 | Rutgers (NJ) | 6 | New Brunswick, NJ | Rutgers 6t,5s - City College of New York 9s |
| 1878 | T | Columbia (NY) | 0 | Stevens Tech (NJ) | 0 | ? | Columbia 0 - Stevens Tech 0 |
| 1878 | T | Columbia (NY) | 0 | Pennsylvania | 0 | Hoboken, NJ | Columbia 8s - Pennsylvania 2s |
| 1878 | W | Harvard (MA) | 3 | Amherst (MA) | 0 | Amherst, MA | Harvard 3g,6t - Amherst 0 |
| 1878 | L | Harvard (MA) | 0 | Princeton (NJ) | 1 | Princeton, NJ | Princeton 1t,4s - Harvard 5s |
| 1878 | L | Harvard (MA) | 0 | Yale (CT) | 1 | Boston, MA | Yale 1g,7s - Harvard 13s |
| 1878 | L | Pennsylvania | 0 | Princeton (NJ) | 2 | Princeton, NJ | Princeton 2g,4t - Pennsylvania 0 |
| 1878 | W | Pennsylvania | 9 | Swarthmore (PA) | 0 | Philadelphia, PA | Pennsylvania 9g,16t - Swarthmore 0 |
| 1878 | L | Pennsylvania | 1 | Princeton (NJ) | 2 | Philadelphia, PA | Princeton 2g,5t - Pennsylvania 1g |
| 1878 | T | Pennsylvania | 0 | Columbia (NY) | 0 | Hoboken, NJ | Columbia 8s - Pennsylvania 2s |
| 1878 | W | Princeton (NJ) | 2 | Pennsylvania | 0 | Princeton, NJ | Princeton 2g,4t - Pennsylvania 0 |
| 1878 | W | Princeton (NJ) | 4 | Stevens Tech (NJ) | 0 | Princeton, NJ | Princeton 4g,6t - Stevens Tech 0 |
| 1878 | W | Princeton (NJ) | 5 | Rutgers (NJ) | 0 | Princeton, NJ | Princeton 5g,8t - Rutgers 0 |
| 1878 | W | Princeton (NJ) | 2 | Pennsylvania | 1 | Philadelphia, PA | Princeton 2g,5t - Pennsylvania 1g |
| 1878 | W | Princeton (NJ) | 1 | Harvard (MA) | 0 | Princeton, NJ | Princeton 1t,4s - Harvard 5s |
| 1878 | W | Princeton (NJ) | 1 | Yale (CT) | 0 | Hoboken, NJ | Princeton 1g,7s - Yale 2s |
| 1878 | T | Rutgers (NJ) | 0 | Stevens Tech (NJ) | 0 | New Brunswick, NJ | Stevens Tech 0 - Rutgers 0 |
| 1878 | L | Rutgers (NJ) | 0 | Princeton (NJ) | 5 | Princeton, NJ | Princeton 5g,8t - Rutgers 0 |
| 1878 | L | Rutgers (NJ) | 0 | Stevens Tech (NJ) | 1 | Hoboken, NJ | Stevens Tech 1g - Rutgers 0 |
| 1878 | W | Rutgers (NJ) | 6 | City College of New York | 0 | New Brunswick, NJ | Rutgers 6t,5s - City College of New York 9s |
| 1878 | L | Seawanhakas Football Club (NY) | 0 | City College of New York | 7 | ? | City College of New York 7g,7t - Seawanhakas Football Club 0 |
| 1878 | L | Stevens Tech (NJ) | 0 | Princeton (NJ) | 4 | Princeton, NJ | Princeton 4g,6t - Stevens Tech 0 |
| 1878 | T | Stevens Tech (NJ) | 0 | Rutgers (NJ) | 0 | New Brunswick, NJ | Stevens Tech 0 - Rutgers 0 |
| 1878 | T | Stevens Tech (NJ) | 0 | Columbia (NY) | 0 | ? | Columbia 0 - Stevens Tech 0 |
| 1878 | W | Stevens Tech (NJ) | 1 | Rutgers (NJ) | 0 | Hoboken, NJ | Stevens Tech 1g - Rutgers 0 |
| 1878 | L | Swarthmore (PA) | 0 | Pennsylvania | 9 | Philadelphia, PA | Pennsylvania 9g,16t - Swarthmore 0 |
| 1878 | L | Trinity (CT) | 0 | Yale (CT) | 2 | Hartford, CT | Yale 2g,10t - Trinity 0 |
| 1878 | L | Trinity (CT) | 0 | Yale (CT) | 2 | Hartford, CT | Yale 2g,4t,2s - Trinity 0 |
| 1878 | L | Williston Seminary (MA) | 0 | Amherst (MA) | 1 | ? | Amherst 1g,2t - Williston Academy 0 |
| 1878 | W | Yale (CT) | 2 | Amherst (MA) | 0 | New Haven, CT | Yale 2g,3t - Amherst 0 |
| 1878 | W | Yale (CT) | 2 | Trinity (CT) | 0 | Hartford, CT | Yale 2g,10t - Trinity 0 |
| 1878 | W | Yale (CT) | 2 | Trinity (CT) | 0 | Hartford, CT | Yale 2g,4t,2s - Trinity 0 |
| 1878 | T | Yale (CT) | 0 | Amherst (MA) | 0 | ? | Amherst 13s - Yale 1s |
| 1878 | W | Yale (CT) | 1 | Harvard (MA) | 0 | Boston, MA | Yale 1g,7s - Harvard 13s |
| 1878 | L | Yale (CT) | 0 | Princeton (NJ) | 1 | Hoboken, NJ | Princeton 1g,7s - Yale 2s |